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The terminal immunoglobulin-like repeats of LigA and LigB of Leptospira enhance their binding to gelatin binding domain of fibronectin and host cells.

Leptospira spp. are pathogenic spirochetes that cause the zoonotic disease leptospirosis. Leptospiral immunoglobulin (Ig)-like protein B (LigB) contributes to the binding of Leptospira to extracellular matrix proteins such as fibronectin, fibrinogen, laminin, elastin, tropoelastin and collagen. A hi...

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Bibliografiske detaljer
Principais autores: Yi-Pin Lin, Sean P McDonough, Yogendra Sharma, Yung-Fu Chang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2010-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC2892007?pdf=render
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