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In Silico identification and modelling of FDA-approved drugs targeting T-type calcium channels.

Studies have shown that inhibition of the Cav3.1 T-type calcium channel can prevent or suppress neurological diseases, such as epileptic seizures and diabetic neuropathy. In this study, we aimed to use in silico simulations to identify a U.S. Food and Drug Administration (FDA)-approved drug that can...

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Autors principals: Pedro Fong, Susana Roman Garcia, Melanie I Stefan, David C Sterratt
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2025-01-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0327386
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