Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
Mutations that allow SIV/HIV to avoid the cytotoxic T lymphocyte (CTL) response are well documented. Recently, there have been a few attempts at estimating the costs of CTL escape mutations in terms of the reduction in viral fitness and the killing rate at which the CTL response specific to one vira...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2006-03-01
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| Serie: | PLoS Computational Biology |
| Accesso online: | http://europepmc.org/articles/PMC1420660?pdf=render |
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