Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas

Estrogen receptor alpha-positive (ERα+) luminal tumors are the most frequent subtype of breast cancer. Stat1−/− mice develop mammary tumors that closely recapitulate the biological characteristics of this cancer subtype. To identify transforming events that contribute to tumorigenesis, we performed...

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Autors principals:	Obi L. Griffith, Szeman Ruby Chan, Malachi Griffith, Kilannin Krysiak, Zachary L. Skidmore, Jasreet Hundal, Julie A. Allen, Cora D. Arthur, Daniele Runci, Mattia Bugatti, Alexander P. Miceli, Heather Schmidt, Lee Trani, Krishna-Latha Kanchi, Christopher A. Miller, David E. Larson, Robert S. Fulton, William Vermi, Richard K. Wilson, Robert D. Schreiber, Elaine R. Mardis
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2016-09-01
Col·lecció:	Cell Reports
Matèries:	breast cancer estrogen-receptor positive luminal STAT1 mouse model whole genome sequencing PRLR
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S221112471631172X
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