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Crosstalk between CD4 T cells and synovial fibroblasts from human arthritic joints promotes hyaluronan-dependent leukocyte adhesion and inflammatory cytokine expression in vitro

The content and organization of hyaluronan (HA) in the extracellular matrix (ECM) have been identified as strong indicators of inflammation in joint disease, although the source and role of HA as an effector of inflammation is not clear. In this study, we established co-cultures of activated human C...

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Principais autores: Inkyung Kang, Christian Hundhausen, Stephen P. Evanko, Prasanthi Malapati, Gail Workman, Christina K. Chan, Cliff Rims, Gary S. Firestein, David L. Boyle, Kevin M. MacDonald, Jane H. Buckner, Thomas N. Wight
格式: Artigo
語言:Inglês
出版: Elsevier 2022-06-01
叢編:Matrix Biology Plus
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在線閱讀:http://www.sciencedirect.com/science/article/pii/S2590028522000102
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