Biomimetic Silica Particles with Self-Loading BMP-2 Knuckle Epitope Peptide and Its Delivery for Bone Regeneration

Biomimetic silica deposition is an in-situ immobilization method for bioactive molecules under biocompatible conditions. The osteoinductive P4 peptide derived from the knuckle epitope of bone morphogenetic protein (BMP), which binds to BMP receptor-II (BMPRII), has been newly found to contain silica...

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Detalhes bibliográficos

Principais autores:	Mi-Ran Ki, Thi Khoa My Nguyen, Tae-In Park, Hae-Min Park, Seung Pil Pack
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-03-01
coleção:	Pharmaceutics
Assuntos:	BMP2 BMP2 knuckle epitope residues P4 peptide biomimetic silica deposition drug delivery controlled release
Acesso em linha:	https://www.mdpi.com/1999-4923/15/4/1061
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