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Maintenance of pluripotency-like signature in the entire ectoderm leads to neural crest stem cell potential

Abstract The ability of the pluripotent epiblast to contribute progeny to all three germ layers is thought to be lost after gastrulation. The later-forming neural crest (NC) rises from ectoderm and it remains poorly understood how its exceptionally high stem-cell potential to generate mesodermal- an...

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Autori principali: Ceren Pajanoja, Jenny Hsin, Bradley Olinger, Andrew Schiffmacher, Rita Yazejian, Shaun Abrams, Arvydas Dapkunas, Zarin Zainul, Andrew D. Doyle, Daniel Martin, Laura Kerosuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2023-09-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-023-41384-6
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