Vascular smooth muscle–specific YAP/TAZ deletion triggers aneurysm development in mouse aorta

Inadequate adaption to mechanical forces, including blood pressure, contributes to development of arterial aneurysms. Recent studies have pointed to a mechanoprotective role of YAP and TAZ in vascular smooth muscle cells (SMCs). Here, we identified reduced expression of YAP1 in human aortic aneurysm...

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Detalles Bibliográficos

Principais autores:	Marycarmen Arévalo Martínez, Olivia Ritsvall, Joakim Armstrong Bastrup, Selvi Celik, Gabriel Jakobsson, Fatima Daoud, Christopher Winqvist, Anders Aspberg, Catarina Rippe, Lars Maegdefessel, Alexandru Schiopu, Thomas A. Jepps, Johan Holmberg, Karl Swärd, Sebastian Albinsson
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical investigation 2023-09-01
Series:	JCI Insight
Assuntos:	Cell biology Vascular biology
Acceso en liña:	https://doi.org/10.1172/jci.insight.170845
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