Systematic approach for assessing whether undeletable chromosomal regions in Saccharomyces cerevisiae are required for cell viability

Abstract Previously, we identified 49 undeletable chromosomal regions harboring only non-essential genes in the genome of Saccharomyces cerevisiae. We proposed that there might be unknown synthetic lethal combinations of genes present in such undeletable regions of the genome. In this study, we chos...

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Detalhes bibliográficos

Principais autores:	Naim Hassan, Farhana Easmin, Yu Sasano, Keisuke Ekino, Hisataka Taguchi, Satoshi Harashima
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2020-04-01
coleção:	AMB Express
Assuntos:	Undeletable regions Synthetic lethality Mini-chromosome loss Yeast
Acesso em linha:	http://link.springer.com/article/10.1186/s13568-020-01001-x
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