LINE-1 regulates cortical development by acting as long non-coding RNAs

Abstract Long Interspersed Nuclear Elements-1s (L1s) are transposable elements that constitute most of the genome’s transcriptional output yet have still largely unknown functions. Here we show that L1s are required for proper mouse brain corticogenesis operating as regulatory long non-coding RNAs....

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Auteurs principaux:	Damiano Mangoni, Alessandro Simi, Pierre Lau, Alexandros Armaos, Federico Ansaloni, Azzurra Codino, Devid Damiani, Lavinia Floreani, Valerio Di Carlo, Diego Vozzi, Francesca Persichetti, Claudio Santoro, Luca Pandolfini, Gian Gaetano Tartaglia, Remo Sanges, Stefano Gustincich
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2023-08-01
Collection:	Nature Communications
Accès en ligne:	https://doi.org/10.1038/s41467-023-40743-7
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