The dual antioxidant chitosan oligosaccharides regulate the transdifferentiation of lung effector cells in the management of idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with limited treatment options. This study investigates the therapeutic potential of chitosan oligosaccharides (COS), a natural carbohydrate with antioxidant properties, in comparison to the FDA-approved drug pirfenidone (PFD). B...

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Bibliografiske detaljer

Principais autores:	Huan He, Youtao Xu, Xinru Chen, Jiawen Wu, Xianpeng Zhong, Xiyu Li, Jing Qiao
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2025-06-01
Serier:	Carbohydrate Polymer Technologies and Applications
Fag:	Idiopathic pulmonary fibrosis Chitosan oligosaccharides Epithelial‒mesenchymal transition;, Fibroblast‒myofibroblast transition Oxidative stress
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2666893925001203
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