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Reactive Oxygen Species (ROS) Drive Osteocyte Dysfunction in Diabetic Osteoporosis by Impairing Autophagy and Triggering Apoptosis

This study investigates the mechanisms underlying osteocyte injury in a high glucose (HG) environment and explores potential therapeutic targets and diagnostic markers for diabetic osteoporosis, a common complication of type 2 diabetes mellitus (T2DM). Hyperglycemia induces oxidative stress through...

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Principais autores: Mengqi Han, Minyue Zhao, Furong Bai, Mengying Wang, Bo Zhang, Jianfeng Shi, Zhongbo Liu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-10-01
coleção:Antioxidants
Assuntos:
diabetic osteoporosis
hyperglycemia
osteocytes
oxidative stress
reactive oxygen species
autophagy
Acesso em linha:https://www.mdpi.com/2076-3921/14/11/1306
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