IAPP - oligomerisation levels in plasma of people with type 2 diabetes

Abstract Islet amyloid polypeptide (IAPP) is co-secreted with insulin from pancreatic ß-cells. Its oligomerisation is regarded as disease driving force in type 2 diabetes (T2D) pathology. Up to now, IAPP oligomers have been detected in affected tissues. IAPP oligomer concentrations in blood have not...

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Bibliographic Details

Main Authors:	Fabian Rehn, Victoria Kraemer-Schulien, Tuyen Bujnicki, Oliver Bannach, Diethelm Tschoepe, Bernd Stratmann, Dieter Willbold
Format:	Artigo
Language:	Inglês
Published:	Nature Portfolio 2024-08-01
Series:	Scientific Reports
Subjects:	IAPP Diabetes Disease driven protein expression Oligomers sFIDA
Online Access:	https://doi.org/10.1038/s41598-024-70255-3
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