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Enhanced dentate gyrus synaptic plasticity but reduced neurogenesis in a mouse model of amyloidosis

Long-term potentiation (LTP) and neurogenesis in the dentate gyrus (DG) are correlated forms of hippocampal plasticity which share, under physiological conditions, common regulatory mechanisms. In Alzheimer's disease (AD), their alterations are potentially associated with the early cellular patholog...

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Autors principals: Raphaël Poirier, Inge Veltman, Marie Claire Pflimlin, Frédéric Knoflach, Friedrich Metzger
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2010-11-01
Col·lecció:Neurobiology of Disease
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S096999611000210X
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