Neoadjuvant chemoradiotherapy with or without PD-1/PD-L1 inhibitors in locally advanced rectal cancer: a systematic review and meta-analysis

Abstract Background Locally advanced rectal cancer (LARC) represents a pivotal stage of rectal cancer where it is possible to completely cure the cancer before its systemic spread, thus often requiring an aggressive multimodal therapy. Recent trials suggest that programmed cell death protein 1 (PD-1...

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主要な著者:	Muhammad Ansab, Sepideh Razi, Farwa Nisa, Eiman Araib, Shree Rath, Iqra Khan, Noor Ul Huda Ramzan, Esha Dilawar, Anwaar Saeed
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-07-01
シリーズ:	BMC Cancer
主題:	Locally advanced rectal cancer PD-1 inhibitors Neoadjuvant chemoradiotherapy Pathological complete response Immunotherapy Clinical complete response
オンライン･アクセス:	https://doi.org/10.1186/s12885-025-14482-5
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