Activation of ventral tegmental area vesicular GABA transporter (Vgat) neurons alleviates social defeat stress-induced anxiety in APP/PS1 mice

IntroductionAlzheimer’s disease (AD) is a progressive neurodegenerative disease that results in cognitive impairment and is often accompanied by anxiety. In this study, we investigated whether the activation of VTAVgat neurons could reduce anxiety in APP/PS1 mice. We hypothesized that acute social d...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Di Yao, Rong Li, Musa Kora, Hongqing Huang, Xinghua Liu, Song Gong
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2023-03-01
Rangatū:	Frontiers in Aging Neuroscience
Ngā marau:	Alzheimer’s disease social defeat stress model ventral tegmental area (VTA) GABA neuron sleep
Urunga tuihono:	https://www.frontiersin.org/articles/10.3389/fnagi.2023.1142055/full
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!