S100A4 contributes to colorectal carcinoma aggressive behavior and to chemoradiotherapy resistance in locally advanced rectal carcinoma

Abstract To investigate the functional role of S100A4 in advanced colorectal carcinoma (Ad-CRC) and locally advanced rectal carcinoma (LAd-RC) receiving neoadjuvant chemoradiotherapy (NCRT). We analyzed histopathological and immunohistochemical sections from 150 patients with Ad-CRC and 177 LAd-RC p...

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Detalhes bibliográficos

Principais autores:	Yohei Harada, Sayako Ikeda, Yuna Kawabe, Yasuko Oguri, Miki Hashimura, Ako Yokoi, Akiko Sida, Naomi Fukagawa, Misato Hayashi, Mototsugu Ono, Chika Kusano, Hiroyuki Takahashi, Makoto Saegusa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-12-01
Colecção:	Scientific Reports
Assuntos:	S100A4 p53 Apoptosis Colorectal carcinoma Neoadjuvant chemoradiotherapy
Acesso em linha:	https://doi.org/10.1038/s41598-024-82814-9
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