Synthesis and In Vitro Antimycobacterial Activity of Novel N-Arylpiperazines Containing an Ethane-1,2-diyl Connecting Chain

Novel 1-(2-{3-/4-[(alkoxycarbonyl)amino]phenyl}-2-hydroxyethyl)-4-(2-fluorophenyl)-piperazin-1-ium chlorides (alkoxy = methoxy to butoxy; 8a–h) have been designed and synthesized through multistep reactions as a part of on-going research programme focused on finding new antimycobacterials. Lipophili...

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Váldodahkkit:	Tomáš Goněc, Ivan Malík, Jozef Csöllei, Josef Jampílek, Jiřina Stolaříková, Ivan Solovič, Peter Mikuš, Stanislava Keltošová, Peter Kollár, Jim O’Mahony, Aidan Coffey
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	MDPI AG 2017-11-01
Ráidu:	Molecules
Fáttát:	N-arylpiperazines arylaminoethanols lipophilicity electronic properties Mycobacterium tuberculosis H37Rv
Liŋkkat:	https://www.mdpi.com/1420-3049/22/12/2100
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