Glucocorticoid Exposure of Preimplantation Embryos Increases Offspring Anxiety-Like Behavior by Upregulating miR-211-5p via Trpm1 Demethylation

Most studies on mechanisms by which prenatal stress affects offspring behavior were conducted during late pregnancy using in vivo models; studies on the effect of preimplantation stress are rare. In vivo models do not allow accurate specification of the roles of different hormones and cells within t...

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Detalhes bibliográficos

Principais autores:	Hong-Jie Yuan, Xiao Han, Guo-Liang Wang, Jia-Shun Wu, Nan He, Jie Zhang, Qiao-Qiao Kong, Shuai Gong, Ming-Jiu Luo, Jing-He Tan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-04-01
Colecção:	Frontiers in Cell and Developmental Biology
Assuntos:	anxiety glucocorticoids miR-211-5p preimplantation embryos Trpm1
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2022.874374/full
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