Polygenic risk for Alzheimer's disease is associated with neuroaxonal damage before onset of clinical symptoms

Abstract INTRODUCTION Establishing valid diagnostic strategies is a precondition for successful therapeutic intervention in Alzheimer's disease (AD). METHODS One hundred forty‐four healthy 75‐year‐old participants from the Vienna‐Transdanube‐Aging longitudinal cohort study were tested for neuroaxona...

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Váldodahkkit:	Sonja M. Kagerer, Swapnil Awasthi, Stephan Ripke, Aleksandra Maceski, Pascal Benkert, Aïda B. Fall, Peter Riederer, Peter Fischer, Susanne Walitza, Edna Grünblatt, Jens Kuhle, Paul G. Unschuld
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Wiley 2024-01-01
Ráidu:	Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Fáttát:	Alzheimer's disease genome‐wide association studies neurofilament light chain plasma biomarker polygenic risk score single molecular array
Liŋkkat:	https://doi.org/10.1002/dad2.12504
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