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Maternal Western diet programs persistent transcriptomic signatures in offspring PBMCs that are largely reversible by interventions during lactation

Maternal consumption of a Western diet (WD) during critical developmental periods has been shown to program long-term metabolic dysfunction in offspring. However, it remains unclear whether these early exposures leave a persistent transcriptomic imprint into adulthood and whether this signature can...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Catalina A. Pomar, Ana Valle, Antoni Caimari, Andreu Palou, Mariona Palou, Catalina Picó
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2026-07-01
Rangatū:Frontiers in Nutrition
Ngā marau:
leptin
maternal obesity
metabolic programming
obesogenic diets
transcriptomic
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fnut.2026.1892621/full
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