Multi-regulatory potency of USP1 on inflammasome components promotes pyroptosis in thyroid follicular cells and contributes to the progression of Hashimoto's thyroiditis

Abstract Background Inflammatory diseases are often initiated by the activation of inflammasomes triggered by pathogen-associated molecular patterns (PAMPs) and endogenous damage-associated molecular patterns (DAMPs), which mediate pyroptosis. Although pyroptosis resulting from aberrant inflammasome...

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Detalhes bibliográficos

Principais autores:	Xuying Zhao, Wenyu Ni, Wenjie Zheng, Wenkai Ni, Chunfeng Sun, Yunjuan Gu, Zhifeng Gu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-08-01
coleção:	Molecular Medicine
Assuntos:	USP1 Inflammasome Pyroptosis Thyroid follicular cells Hashimoto's thyroiditis
Acesso em linha:	https://doi.org/10.1186/s10020-024-00885-w
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