Persistent memory despite rapid contraction of circulating T Cell responses to SARS-CoV-2 mRNA vaccination

IntroductionWhile antibodies raised by SARS-CoV-2 mRNA vaccines have had compromised efficacy to prevent breakthrough infections due to both limited durability and spike sequence variation, the vaccines have remained highly protective against severe illness. This protection is mediated through cellu...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ellie Taus, Christian Hofmann, F. Javier Ibarrondo, Laura S. Gong, Mary Ann Hausner, Jennifer A. Fulcher, Paul Krogstad, Scott G. Kitchen, Kathie G. Ferbas, Nicole H. Tobin, Anne W. Rimoin, Grace M. Aldrovandi, Otto O. Yang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-02-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	SARS-CoV-2 cellular immunity T cells elispot intracellular cytokine staining SARS-CoV-2 mRNA vaccines
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1100594/full
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