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Metabolic Effect of Estrogen Receptor Agonists on Breast Cancer Cells in the Presence or Absence of Carbonic Anhydrase Inhibitors

Metabolic shift is one of the major hallmarks of cancer development. Estrogen receptor (ER) activity has a profound effect on breast cancer cell growth through a number of metabolic changes driven by its effect on transcription of several enzymes, including carbonic anhydrases, Stearoyl-CoA desatura...

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Autori principali: Anissa Belkaid, Miroslava Čuperlović-Culf, Mohamed Touaibia, Rodney J. Ouellette, Marc E. Surette
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2016-05-01
Serie:Metabolites
Soggetti:
17β-estradiol
ferulic acid
carbonic anhydrase
ER + cells
metabolomics
cancer metabolism
acetazolamide
Accesso online:http://www.mdpi.com/2218-1989/6/2/16
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