Chronic Binge Alcohol Administration Dysregulates Hippocampal Genes Involved in Immunity and Neurogenesis in Simian Immunodeficiency Virus-Infected Macaques

Alcohol use disorders (AUD) exacerbate neurocognitive dysfunction in Human Immunodeficiency Virus (HIV+) patients. We have shown that chronic binge alcohol (CBA) administration (13–14 g EtOH/kg/wk) prior to and during simian immunodeficiency virus (SIV) infection in rhesus macaques unmasks learning...

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Auteurs principaux:	John K. Maxi, Matt Dean, Jovanny Zabaleta, Krzysztof Reiss, Gregory J. Bagby, Steve Nelson, Peter J. Winsauer, Francesca Peruzzi, Patricia E. Molina
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2016-11-01
Collection:	Biomolecules
Sujets:	SIV alcohol macaque hippocampus neural progenitor cells Tat microarray neuroinflammation neurogenesis
Accès en ligne:	http://www.mdpi.com/2218-273X/6/4/43
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