The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Abstract Multiple prenatal adverse environmental factors alter hepatic cytochrome P450 (CYP) enzymes expression in offspring, with these changes persisting after birth. These factors induce fetal exposure to excessive maternal glucocorticoids (GCs), however, the mechanisms by which intrauterine GCs...

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Bibliografiske detaljer

Principais autores:	Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo
Format:	Artigo
Sprog:	Inglês
Udgivet:	Wiley 2026-01-01
Serier:	Advanced Science
Fag:	constitutive androstane receptor cytochrome P450 epigenetic modification glucocorticoids glucocorticoid receptor
Online adgang:	https://doi.org/10.1002/advs.202515583
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