Whole-Cell Photobleaching Reveals Time-Dependent Compartmentalization of Soluble Proteins by the Axon Initial Segment

By limiting protein exchange between the soma and the axon, the axon initial segment (AIS) enables the segregation of specific proteins and hence the differentiation of the somatodendritic compartment and the axonal compartment. Electron microscopy and super-resolution fluorescence imaging have prov...

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Bibliografske podrobnosti

Principais autores:	LaShae Nicholson, Nicolas Gervasi, Thibault Falières, Adrien Leroy, Dorian Miremont, Diana Zala, Cyril Hanus
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2020-07-01
Serija:	Frontiers in Cellular Neuroscience
Teme:	neuronal polarity protein compartmentalization axon initial segment correlative imaging super-resolution fluorescence loss in photobleaching
Online dostop:	https://www.frontiersin.org/article/10.3389/fncel.2020.00180/full
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