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Evaluation of DNA damage induced by perfluorooctanoic acid using acellular, cellular, and in vivo comet assays

ObjectiveTo examine perfluorooctanoic acid (PFOA)-induced DNA damage using a combined in vivo and in vitro experiment.MethodsAcellular nuclear DNA damage was used as a model to test the damage induced by exposure to 0.00, 0.13, 0.25, and 0.50 mmol/L PFOA for 1 h. The YAC-1 cell was used as the resea...

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Detalhes bibliográficos
Principais autores: WANG Qian, XU Tongguang, WANG Tianwei, CHEN Huihui, ZHANG Wenzhong
Formato: Artigo
Idioma:Chinês
Publicado em: The Editorial Office of Chinese Journal of Food Hygiene 2023-07-01
coleção:Zhongguo shipin weisheng zazhi
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Acesso em linha:http://www.zgspws.com/zgspwszz/article/abstract/202307002
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