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Candida albicans Shed Msb2 and Host Mucins Affect the Candidacidal Activity of Salivary Hst 5

Salivary Histatin 5 (Hst 5) is an antimicrobial peptide that exhibits potent antifungal activity towards Candida albicans, the causative agent of oral candidiasis. However, it exhibits limited activity in vivo, largely due to inactivation by salivary components of both host and pathogen origin. Prot...

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Principais autores: Sumant Puri, Justin Friedman, Darpan Saraswat, Rohitashw Kumar, Rui Li, Donna Ruszaj, Mira Edgerton
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2015-10-01
Serier:Pathogens
Fag:
Candida albicans
oral candidiasis
Histatin 5
saliva
mucins
secreted aspartyl proteases
Online adgang:http://www.mdpi.com/2076-0817/4/4/752
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