Blockade of XCL1/Lymphotactin Ameliorates Severity of Periprosthetic Osteolysis Triggered by Polyethylene-Particles

Periprosthetic osteolysis induced by orthopedic implant-wear particles continues to be the leading cause of arthroplasty failure in majority of patients. Release of the wear debris results in a chronic local inflammatory response typified by the recruitment of immune cells, including macrophages. Th...

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Autors principals:	Yuan Tian, Mohamad Alaa Terkawi, Tomohiro Onodera, Hend Alhasan, Gen Matsumae, Daisuke Takahashi, Masanari Hamasaki, Taku Ebata, Mahmoud Khamis Aly, Hiroaki Kida, Tomohiro Shimizu, Keita Uetsuki, Ken Kadoya, Norimasa Iwasaki
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2020-08-01
Col·lecció:	Frontiers in Immunology
Matèries:	periprosthetic osteolysis XCL1 polyethylene wear debris osteoclasts osteoblasts
Accés en línia:	https://www.frontiersin.org/article/10.3389/fimmu.2020.01720/full
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