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Low Glucose Mediated Fluconazole Tolerance in <i>Cryptococcus neoformans</i>

Chronic meningoencephalitis is caused by <i>Cryptococcus neoformans</i> and is treated in many parts of the world with fluconazole (FLC) monotherapy, which is associated with treatment failure and poor outcome. In the host, <i>C. neoformans</i> propagates predominantly under low glucose growth condi...

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Hlavní autoři: Somanon Bhattacharya, Natalia Kronbauer Oliveira, Anne G. Savitt, Vanessa K. A. Silva, Rachel B. Krausert, Berhane Ghebrehiwet, Bettina C. Fries
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2021-06-01
Edice:Journal of Fungi
Témata:
azole resistance
efflux pumps
fungal pathogenesis
cryptococcosis
low glucose
glucose starvation
On-line přístup:https://www.mdpi.com/2309-608X/7/6/489
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