Ectopic Leptin Production by Intraocular Pancreatic Islet Organoids Ameliorates the Metabolic Phenotype of <i>ob/ob</i> Mice

The pancreatic islets of Langerhans consist of endocrine cells that secrete peptide hormones into the blood circulation in response to metabolic stimuli. When transplanted into the anterior chamber of the eye (ACE), pancreatic islets engraft and maintain morphological features of native islets as we...

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Главные авторы:	Barbara Leibiger, Tilo Moede, Ismael Valladolid-Acebes, Meike Paschen, Montse Visa, Ingo B. Leibiger, Per-Olof Berggren
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2021-06-01
Серии:	Metabolites
Предметы:	pancreatic islets leptin exocytosis tissue-engineering in vivo imaging metabolism
Online-ссылка:	https://www.mdpi.com/2218-1989/11/6/387
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