Upregulation of GSTP1 mediated by chimeric TFE3 promotes TFE3-tRCC progression by targeting JNK signaling pathway

Abstract Background TFE3-translocation renal cell carcinoma (TFE3-tRCC), a distinct subtype of kidney cancer characterized by Xp11.2 translocations, involving TFE3 fusion with various partner genes, lacks effective treatments and prognostic biomarkers for advanced stages. This study aimed to unravel...

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Detalhes bibliográficos

Principais autores:	Weixu Chen, Mengtong Wu, Lin Du, Changhua Fang, Hao Wang, Wendi Wang, Chengwei Zhang, Hongqian Guo, Gutian Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-12-01
coleção:	World Journal of Surgical Oncology
Assuntos:	TFE3-tRCC GSTP1 ASPL-TFE3 JNK signaling pathway Ezatiostat
Acesso em linha:	https://doi.org/10.1186/s12957-024-03633-w
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