Second-site suppressors of HIV-1 capsid mutations: restoration of intracellular activities without correction of intrinsic capsid stability defects

<p>Abstract</p> <p>Background</p> <p>Disassembly of the viral capsid following penetration into the cytoplasm, or uncoating, is a poorly understood stage of retrovirus infection. Based on previous studies of HIV-1 CA mutants exhibiting altered capsid stability, we concluded that formation of a capsi...

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Principais autores:	Yang Ruifeng, Shi Jiong, Byeon In-Ja L, Ahn Jinwoo, Sheehan Jonathan H, Meiler Jens, Gronenborn Angela M, Aiken Christopher
格式:	Artigo
语言:	Inglês
出版:	BMC 2012-04-01
丛编:	Retrovirology
主题:	HIV-1 Capsid Uncoating Suppressor mutations Inhibitor
在线阅读:	http://www.retrovirology.com/content/9/1/30
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