Recurrence risk prediction in resected stage I-III melanoma utilizing circulating tumor DNA

Abstract Background Adjuvant therapies are now considered standard care for high-risk melanoma patients. It is urgent to identify reliable biomarkers to select patients at high risk of relapse, who will derive more benefit from adjuvant therapy. Methods Targeted next-generation sequencing using a 43...

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Autori principali:	Mengke Zhao, Lianjun Zhao, Yueling Yang, Fufeng Wang, Jiani Yin, Xiaoying Wu, Yu Ren, Xinyu Su, Yirong Wu, Luqiao Li, Rong Huang, Kelin Zheng, JiaYu Wang, Zhengyun Zou
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-11-01
Serie:	BMC Cancer
Soggetti:	Resectable melanoma Recurrence risk Postsurgical ctdna Predictive biomarkers Chromosomal instability
Accesso online:	https://doi.org/10.1186/s12885-025-15093-w
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