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The LncRNA MIR503HG/miR-224-5p/TUSC3 Signaling Cascade Suppresses Gastric Cancer Development via Modulating ATF6 Branch of Unfolded Protein Response

BackgroundUnfolded protein response (UPR)-mediated tumor-promoting functions have been identified in multiple cancers, and this study focused on investigating the role and molecular mechanisms of UPR in modulating gastric cancer (GC) pathogenesis.MethodsThe bioinformatics analysis was performed to e...

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Principais autores: Han Lin, Jinge Wang, Tong Wang, Jiaming Wu, Peng Wang, Xiaoyan Huo, Jun Zhang, Huayang Pan, Yuying Fan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-07-01
coleção:Frontiers in Oncology
Assuntos:
unfolded protein response
gastric cancer
LncRNA MIR503HG
miR-224-5p
TUSC3
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2021.708501/full
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