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Growth-uncoupled isoprenoid synthesis in Rhodobacter sphaeroides

Abstract Background Microbial cell factories are usually engineered and employed for cultivations that combine product synthesis with growth. Such a strategy inevitably invests part of the substrate pool towards the generation of biomass and cellular maintenance. Hence, engineering strains for the f...

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Autori principali: Enrico Orsi, Ioannis Mougiakos, Wilbert Post, Jules Beekwilder, Marco Dompè, Gerrit Eggink, John van der Oost, Servé W. M. Kengen, Ruud A. Weusthuis
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-07-01
Serie:Biotechnology for Biofuels
Soggetti:
Rhodobacter sphaeroides
Isoprenoid biosynthesis
PHB
MEP
MVA
Growth-independent production
Accesso online:http://link.springer.com/article/10.1186/s13068-020-01765-1
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