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Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection.

Shigella spp. are pathogenic bacteria that cause bacillary dysentery in humans by invading the colonic and rectal mucosa where they induce dramatic inflammation. Here, we have analyzed the role of the soluble PRR Pentraxin 3 (PTX3), a key component of the humoral arm of innate immunity. Mice that ha...

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Principais autores: Valeria Ciancarella, Luigi Lembo-Fazio, Ida Paciello, Anna-Karin Bruno, Sébastien Jaillon, Sara Berardi, Marialuisa Barbagallo, Shiri Meron-Sudai, Dani Cohen, Antonio Molinaro, Giacomo Rossi, Cecilia Garlanda, Maria Lina Bernardini
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2018-12-01
Serier:PLoS Pathogens
Online adgang:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1007469&type=printable
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