Synergistic and antagonistic drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines

Abstract Acute myeloid leukemia (AML) is the most prevalent type of leukemia in adults. Its heterogeneity, both between patients and within the same patient, is often a factor contributing to poor treatment outcomes. Despite advancements in AML biology and medicine in general, the standard AML treat...

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Hlavní autoři:	Fatma Neslihan Kalkan, Muhammed Sadik Yildiz, N. Ezgi Wood, Michael Farid, Melissa McCoy, Milo M. Lin, Chengcheng Zhang, Bruce A. Posner, Stephen S. Chung, Erdal Toprak
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-06-01
Edice:	Scientific Reports
On-line přístup:	https://doi.org/10.1038/s41598-025-03242-x
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