Transcriptome Analysis of Circulating Immune Cell Subsets Highlight the Role of Monocytes in Zaire Ebola Virus Makona Pathogenesis

Existing models of Ebola virus disease (EVD) suggest antigen-presenting cells are initial targets of Zaire ebolavirus (ZEBOV). In vitro studies have shown that ZEBOV infection of monocytes and macrophages results in the production of inflammatory mediators, which may cause lymphocyte apoptosis. Howe...

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Principais autores:	Andrea R. Menicucci, Krista Versteeg, Courtney Woolsey, Chad E. Mire, Joan B. Geisbert, Robert W. Cross, Krystle N. Agans, Allen Jankeel, Thomas W. Geisbert, Ilhem Messaoudi
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2017-10-01
סדרה:	Frontiers in Immunology
נושאים:	Ebola hemorrhagic fever pathogenesis RNASeq monocytes
גישה מקוונת:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01372/full
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!