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Cardiac specific knock-down of peroxisome proliferator activated receptor α prevents fasting-induced cardiac lipid accumulation and reduces perilipin 2.

While fatty acid metabolism is altered under physiological conditions, alterations can also be maladaptive in diseases such as diabetes and heart failure. Peroxisome Proliferator Activated Receptor α (PPARα) is a transcription factor that regulates fat metabolism but its role in regulating lipid sto...

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Bibliografiske detaljer
Principais autores: Natasha Fillmore, Vincent Hou, Junhui Sun, Danielle Springer, Elizabeth Murphy
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2022-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0265007&type=printable
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