Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

Abstract Background Two acute respiratory distress syndrome (ARDS) trials showed no benefit for statin therapy, though secondary analyses suggest inflammatory subphenotypes may have a differential response to simvastatin. Statin medications decrease cholesterol levels, and low cholesterol has been a...

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Autors principals:	Shaun M. Pienkos, Andrew R. Moore, Jiazhen Guan, Joseph E. Levitt, Michael A. Matthay, Rebecca M. Baron, John Conlon, Daniel F. McAuley, Cecilia M. O’Kane, Angela J. Rogers
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2023-03-01
Col·lecció:	Critical Care
Matèries:	Acute respiratory distress syndrome Sepsis Statins Cholesterol Critical care
Accés en línia:	https://doi.org/10.1186/s13054-023-04387-9
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