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Src promotes tumor cell invasion by hijacking the translation machineries

Summary: The Src oncogene controls cancer cell invasiveness by promoting invadosome formation and extracellular matrix (ECM) degradation. Invadosomes are translational hotspots enriched in the eukaryotic translation initiation factor 3 (eIF3) complex that is mandatory for their maintenance. Here, we...

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Autori principali: Benjamin Bonnard, Anouk Chatefau, Cyril Dourthe, Sylvaine Di Tommaso, Jean-William Dupuy, Isabelle Mahouche, Jacobo Solorzano, Morgane Le Bras, Anne-Aurélie Raymond, Violaine Moreau, Arnaud Jabouille, Anne Blangy, Yvan Martineau, Frédéric Saltel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2026-03-01
Serie:Cell Reports
Soggetti:
CP: molecular biology
CP: cancer
Accesso online:http://www.sciencedirect.com/science/article/pii/S2211124726000677
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