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Group II intron-based gene targeting reactions in eukaryotes.

Mobile group II introns insert site-specifically into DNA target sites by a mechanism termed retrohoming in which the excised intron RNA reverse splices into a DNA strand and is reverse transcribed by the intron-encoded protein. Retrohoming is mediated by a ribonucleoprotein particle that contains t...

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Príomhchruthaitheoirí: Marta Mastroianni, Kazuo Watanabe, Travis B White, Fanglei Zhuang, Jamie Vernon, Manabu Matsuura, John Wallingford, Alan M Lambowitz
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2008-09-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC2518211?pdf=render
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