LBPs NPs suppress breast cancer progression by inhibiting YAP1 expression to induce ferroptosis and alter energy metabolism

Abstract Yes-associated protein 1 (YAP1), a core effector of the Hippo signaling pathway, has garnered increasing attention for its role in ferroptosis signaling in breast cancer. This study investigates the antitumor properties of Lycium barbarum polysaccharides (LBPs) and develops LBPs-loaded poly...

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Bibliographic Details

Main Authors:	Fangfang Zhao, Sen Yang, Ting He, Lijuan Yang, Ting Mo, Juying Kang, Hui Cao, Xiangping Sun, Yang Yu
Format:	Artigo
Language:	Inglês
Published:	Nature Portfolio 2026-02-01
Series:	Scientific Reports
Subjects:	LBPs Nanoparticles Breast cancer YAP1 Ferroptosis
Online Access:	https://doi.org/10.1038/s41598-025-34454-w
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