The Involvement of Sirtuin 1 Dysfunction in High-Fat Diet-Induced Vascular Dysfunction in Mice

High-fat diet (HFD)-induced vascular impairment in mice is associated with a dysfunction of the perivascular adipose tissue (PVAT). The present study was conducted to investigate the involvement of sirtuin 1 (SIRT1). Male C57BL/6J mice were fed an HFD for 20 weeks to induce obesity. Vascular functio...

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Hlavní autoři:	Ning Xia, Gisela Reifenberg, Christian Schirra, Huige Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-03-01
Edice:	Antioxidants
Témata:	perivascular adipose tissue (PVAT) sirtuin 1 (SIRT1) vascular function nicotinamide phosphoribosyltransferase (NAMPT) nicotinamide adenine dinucleotide (NAD<sup>+</sup>) biosynthesis
On-line přístup:	https://www.mdpi.com/2076-3921/11/3/541
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