Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage

Abstract Background Intracerebral hemorrhage (ICH) is a devastating stroke subtype with high mortality and disability, primarily driven by secondary brain injury involving oxidative stress, neuroinflammation, and apoptosis. Molecular hydrogen (H₂) exhibits potent neuroprotective effects; however, it...

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Bibliografische Detailangaben

Hauptverfasser:	Chang-Sheng Ma, Bo Han, Jia-Ru Guo, Jin-Fen Guo, Chang-Ku Shi, Yu-Xi Liu, Wen-Jing Yi, Li-Ying Zhang, Ai-Jun Deng, Ying-Shuai Wang, Mao-Tao He
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-02-01
Schriftenreihe:	Journal of Translational Medicine
Schlagworte:	Intracerebral hemorrhage (ICH) Magnesium silicate nanosheets (MGNs) Hydrogen therapy Neuroprotection Anti-apoptosis Anti-inflammation
Online-Zugang:	https://doi.org/10.1186/s12967-026-07755-5
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