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CagA-dependent expression of anti-inflammatory cytokine IL-13 and TNFRSF member Fn14 in Helicobacter pylori infected gastric cells and tissues

Helicobacter pylori infection is a major driver of gastric cancer, with the CagA oncoprotein promoting chronic inflammation and epithelial injury. However, the overall picture of the cytokine–receptor pathways involved in this process remains unclear. To investigate how CagA modulates epithelial sig...

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Main Authors: Rizki Amalia, Junko Akada, Ayush Khangai, Muhammad Asif Khan, Ricky Indra Alfaray, Kartika Afrida Fauzia, Tomohisa Uchida, Takashi Matsumoto, Ari Fahrial Syam, Muhammad Miftahussurur, Yoshio Yamaoka
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-06-01
Series:Frontiers in Microbiology
Subjects:
CagA
chronic infection
cytokine network
Fn14
Helicobacter pylori
IL-13
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2026.1812604/full
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