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Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining

An array of phenotypically diverse myeloid cells and macrophages (MC&M) resides in the tumor microenvironment, requiring multiplexed detection systems for visualization. Here we report an automated, multiplexed staining approach, named PLEXODY, that consists of five MC&M-related fluorescentl...

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Furkejuvvon:
Váldodahkkit: Joshua Saylor, Zhaoxuan Ma, Helen S. Goodridge, Fangjin Huang, Anne E. Cress, Stephen J. Pandol, Stephen L. Shiao, Adriana C. Vidal, Lily Wu, Nicholas G. Nickols, Arkadiusz Gertych, Beatrice S. Knudsen
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2018-12-01
Ráidu:Frontiers in Immunology
Fáttát:
multiplex
immunofluorescence
immunohistochemistry
macrophage
myeloid
spatial profiling
Liŋkkat:https://www.frontiersin.org/article/10.3389/fimmu.2018.02925/full
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