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Tenuigenin regulates succinylation via SIRT5 for suppressing the tumorigenicity of hepatocellular carcinoma cells

IntroductionTenuigenin (TEN) is an active component extracted from the Polygala tenuifolia root and has been reported to show anti-insomnia, anti- amnesia, neuroprotective, and anti-inflammatory effects. In this study, we aimed to investigate the anti-tumor effects of TEN on hepatocellular carcinoma...

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Autori principali: Yifan Yan, Chang Liu, Jiao Luo, Lianhong Pan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2026-04-01
Serie:Frontiers in Pharmacology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fphar.2026.1756680/full
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